天使之翼

【我们的节日春节】正月初五——迎财神_我的网站

A |     新春携瑞，福满人间          大年初五，迎财神          财神到，好运来          财富滚滚，事业翻倍          福禄双全，幸福美满          恭贺蛇年新春                    接财神          接财神是中国民间古老的传统节日习俗。    

    Qingyangshen, or Root of Auricledleaf Swallowwort, a traditional ethnic medicinal plant long used in Southwest China's Yunnan Province. Photo: Scrrenshot from website
A Chinese research team has identified a new potential target to develop antidepressant drug from Qingyangshen, or Root of Auricledleaf Swallowwort, a traditional ethnic medicinal plant long used in Southwest China's Yunnan Province, according to Kunming University of Science and Technology, Science and Technology Daily reported Sunday.
The team, led by professors Xu Tianrui and Xiang Cheng from the university's School of Life Science and Technology, found that Qingyangshen glycosides, the plant's core active compound, can alleviate depression-related behaviors by simultaneously suppressing inflammation, reducing oxidative damage and stabilizing neurotransmitters in the brain.
The findings were published in the international journal Phytomedicine.  
Depression has become a widespread mental health disorder globally, while existing clinical drugs fail to provide effective treatment for more than 30 percent of patients, according to the researchers. Previous studies have established a strong link between chronic inflammation and depression, but existing anti-inflammatory drugs have limited targeting capabilities, underscoring the need for new therapeutic targets and lead compounds.
Qingyangshen, a plant of the Cynanchum genus in the Apocynaceae family, has long been used as a traditional medicine by ethnic groups including the Naxi, Yi and Bai peoples in Yunnan, mainly for treating neurological conditions such as epilepsy and neurasthenia. 
The researchers systematically examined the pharmacological effects of Qingyangshen extract and its core active compound, Qingyangshen glycosides. Tests using mouse, zebrafish and fruit fly models repeatedly showed that the compound significantly improved depression-related behaviors induced by inflammation, according to the report.
To identify the compound's target, the team developed a dual-discrimination model for four subtypes of prostaglandin E2 receptors and combined it with AI-powered machine learning. The researchers screened hundreds of G protein-coupled receptors and identified the prostaglandin E2 subtype 4 receptor as the direct target of Qingyangshen glycosides.
Multiple molecular experiments confirmed that the compound binds directly to the receptor and acts as an inhibitory ligand. Further experiments involving animals with the receptor knocked out in the hippocampus showed that the antidepressant effects of Qingyangshen glycosides disappeared completely when the receptor was absent, providing the first in-vivo evidence that the receptor is essential for the compound's therapeutic effects.
    An illustration of the research. Photo: Screenshot from the website
The study establishes the prostaglandin E2 subtype 4 receptor as a potential new target for antidepressant drug development and points to a new approach to treating depression through inflammatory pathways. It also identifies Qingyangshen glycosides as a potential lead compound for developing highly targeted anti-inflammatory antidepressants, creating a research chain from ethnic medicinal plants and active compounds to drug targets and new drug development.
Global Times
。因为中国民间传说正月初五是财神的生日，所以过了年初一，接下来最重要的活动就是接财神，在财神生日到来的前一天晚上，各家置办酒席，为财神贺辰。                             迎财神          迎财神盛行于明清和民国时期，财神分为文财神和武财神和君财神。文财神是比干，武财神是赵公明和关羽，君财神是柴王爷。文财神”财帛星君，也称“增福财神”:他的绘像经常与“福”、“禄”、“寿”三星和喜神列在一起，合起来为福、禄、寿、喜、财。财帛星君脸白发长，手捧一个宝盆，“招财进宝”四字由此而来。

B | 一般把财帛星君画像供奉于正厅，祈求财运、福运。         新岁携福至                              巳巳如意，恭贺新春                    送五穷          “五穷”也叫”五鬼”。指”智穷、学穷、文穷、命穷、交穷”等五种穷鬼。这一天，人们黎明即起，放鞭炮，打扫卫生。鞭炮从房间里往门外边走边放，将不吉利和妖魔鬼怪都轰将出去。打扫卫生是一种彻底的大扫除，从每间房屋里把垃圾扫出门外，等到垃圾扫出大门，鞭炮也从屋里放到了屋外，拿一个极大的爆竹，放在垃圾堆上燃放，预示着一切穷气穷鬼都给赶跑了!福、快乐、健康，好运、平安，统统迎进家门口，喜气洋洋过大年，开春工作更积极，生活顺心每一天，全家健康到永远。         放鞭炮          正月初五，家家户户都会放鞭炮，以此驱赶不吉利的事物，包括晦气和妖魔鬼怪，同时也象征着将一切不好的东西从家中抛出。         大扫除          由于春节期间的禁忌，如避免打扫卫生以防扫走好运，到了正月初五，即所谓的“破五”，人们会进行彻底的大扫除，将家中的垃圾和废物清理掉，以迎接财神和新年的好运。         吃饺子          寓意招财进宝、富贵吉祥，也有的地方吃饺子是为了解除过去几天积存下来的晦气。                             禁忌小提示                              ①忌串门          避免将穷气带到亲戚邻里家。         ②不吃莲藕          莲藕有很多孔、意味着“漏财”。         ③不拜年          上门拜年意味着去“抢财。

C |          ④不梳头          好财运从头开始，梳头发时会掉头发。                   2025 HAPPY NEW YEAR          巳巳如意 灵蛇贺岁          财神到，富贵到；          财神到，祥瑞到。         大年初五迎财神，开启一年好运程。         点点幼儿园          祝每个家庭和和美美；          每个孩子健康成长，活泼快乐！                    图文均来自网络                    点点家。

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Published on:08:53:54